Levetiracetam as alternative treatment in Jeavons syndrome

Abstract We report on a 25 year old female patient who had a diagnosis of Jeavons syndrome since her childhood. Although valproate led to seizure freedom, she developed persistent reproductive endocrine disorders attributed to this drug. The withdrawal of valproate in parallel with an initiation of...

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Bibliographic Details
Published in:Journal of the neurological sciences 2014-06, Vol.341 (1), p.147-149
Main Authors: Parissis, D, Ioannidis, P, Karacostas, D
Format: Article
Language:English
Subjects:
Adult
Anticonvulsants - therapeutic use
Epilepsy, Absence - complications
Epilepsy, Absence - drug therapy
Eyelid myoclonia
Female
Humans
Jeavons syndrome
Levetiracetam
Myoclonus - complications
Myoclonus - drug therapy
Neurology
Piracetam - analogs & derivatives
Piracetam - therapeutic use
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Summary:Abstract We report on a 25 year old female patient who had a diagnosis of Jeavons syndrome since her childhood. Although valproate led to seizure freedom, she developed persistent reproductive endocrine disorders attributed to this drug. The withdrawal of valproate in parallel with an initiation of levetiracetam monotherapy resulted in a maintenance of clinical remission and a resolution of these abnormalities. This case together with relevant literature data supports the view that the use of levetiracetam might be of benefit for female patients with Jeavons syndrome.
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2014.03.051