Genotypes of Enterocytozoon bieneusi in Livestock in China: High Prevalence and Zoonotic Potential: e97623

Despite many recent advances in genotype characterization of Enterocytozoon bieneusi worldwide and the exploration of the extent of cross-species transmission of microsporidiosis between humans and animals, the epidemiology of this neglected disease in China is poorly understood. In this study, a ve...

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Bibliographic Details
Published in:PloS one 2014-05, Vol.9 (5)
Main Authors: Li, Wei, Li, Yijing, Li, Weizhi, Yang, Jinping, Song, Mingxin, Diao, Ruinan, Jia, Honglin, Lu, Yixin, Zheng, Jun, Zhang, Xichen
Format: Article
Language:English
Subjects:
Enterocytozoon bieneusi
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Summary:Despite many recent advances in genotype characterization of Enterocytozoon bieneusi worldwide and the exploration of the extent of cross-species transmission of microsporidiosis between humans and animals, the epidemiology of this neglected disease in China is poorly understood. In this study, a very high prevalence (60.3%; 94/156) of E. bieneusi infections in farmed pigs in Jilin province was detected by PCR of the ribosomal internal transcribed spacer (ITS). DNA sequence analysis of 88 E. bieneusi-positive specimens identified 12 distinct genotypes (11 known: CHN7, CS-1, CS-4, CS-6, EbpA, EbpB, EbpC, EbpD, EBITS3, G, and Henan-I; one novel: CS-9). Frequent appearance of mixed genotype infections was seen in the study animals. Weaned (74.6%; 53/71) or pre-weaned (68.8%; 22/32) pigs have infection rates significantly higher than growing pigs (35.8%; 19/53) (p
ISSN:1932-6203
DOI:10.1371/journal.pone.0097623