Performance measurement of PSF modeling reconstruction (True X) on Siemens Biograph TruePoint TrueV PET/CT

Objective The Siemens Biograph TruePoint TrueV (B-TPTV) positron emission tomography (PET) scanner performs 3D PET reconstruction using a system matrix with point spread function (PSF) modeling (called the True X reconstruction). PET resolution was dramatically improved with the True X method. In th...

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Bibliographic Details
Published in:Annals of nuclear medicine 2014-05, Vol.28 (4), p.340-348
Main Authors: Lee, Young Sub, Kim, Jin Su, Kim, Kyeong Min, Kang, Joo Hyun, Lim, Sang Moo, Kim, Hee-Joung
Format: Article
Language:English
Subjects:
Algorithms
Animals
Feasibility Studies
Fluorodeoxyglucose F18
Imaging
Imaging, Three-Dimensional - instrumentation
Imaging, Three-Dimensional - methods
Medicine
Medicine & Public Health
Multimodal Imaging - instrumentation
Multimodal Imaging - methods
Neoplasms, Experimental - diagnostic imaging
Nuclear Medicine
Original Article
Phantoms, Imaging
Positron-Emission Tomography - instrumentation
Positron-Emission Tomography - methods
Rabbits
Radiology
Radiopharmaceuticals
Rats
Signal-To-Noise Ratio
Thigh - diagnostic imaging
Tomography, X-Ray Computed - instrumentation
Tomography, X-Ray Computed - methods
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Summary:Objective The Siemens Biograph TruePoint TrueV (B-TPTV) positron emission tomography (PET) scanner performs 3D PET reconstruction using a system matrix with point spread function (PSF) modeling (called the True X reconstruction). PET resolution was dramatically improved with the True X method. In this study, we assessed the spatial resolution and image quality on a B-TPTV PET scanner. In addition, we assessed the feasibility of animal imaging with a B-TPTV PET and compared it with a microPET R4 scanner. Methods Spatial resolution was measured at center and at 8 cm offset from the center in transverse plane with warm background activity. True X, ordered subset expectation maximization (OSEM) without PSF modeling, and filtered back-projection (FBP) reconstruction methods were used. Percent contrast (% contrast) and percent background variability (% BV) were assessed according to NEMA NU2-2007. The recovery coefficient (RC), non-uniformity, spill-over ratio (SOR), and PET imaging of the Micro Deluxe Phantom were assessed to compare image quality of B-TPTV PET with that of the microPET R4. Results When True X reconstruction was used, spatial resolution was
ISSN:0914-7187
1864-6433
DOI:10.1007/s12149-014-0815-z