High-resolution 3D-MRI of postmortem brain specimens fixed by formalin and gadoteridol

Highlights • Gadoteridol can infiltrate deep into the immersion-fixed brain. • MP-RAGE sequence of brain fixed by gadoteridol-mixed formalin yield a high contrast. • We achieved an acquisition high resolution image of 0.5 mm within 30 min. • MRI of fixed brain is highly compatible in forensic practi...

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Bibliographic Details
Published in:Legal medicine (Tokyo, Japan) Japan), 2014-07, Vol.16 (4), p.218-221
Main Authors: Kanawaku, Yoshimasa, Someya, Satoka, Kobayashi, Tomoya, Hirakawa, Keiko, Shiotani, Seiji, Fukunaga, Tatsushige, Ohno, Youkichi, Kawakami, Saki, Kanetake, Jun
Format: Article
Language:English
Subjects:
Autopsy - methods
Brain
Brain - drug effects
Brain - pathology
Contrast Media
Fixatives
Forensic Pathology - methods
Formaldehyde
Gadolinium
Gadoteridol
Heterocyclic Compounds
Humans
Imaging, Three-Dimensional - methods
Immersion
Internal Medicine
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Neuroimaging - methods
Organometallic Compounds
Postmortem MRI
Specimen
Tokyo
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Summary:Highlights • Gadoteridol can infiltrate deep into the immersion-fixed brain. • MP-RAGE sequence of brain fixed by gadoteridol-mixed formalin yield a high contrast. • We achieved an acquisition high resolution image of 0.5 mm within 30 min. • MRI of fixed brain is highly compatible in forensic practices.
ISSN:1344-6223
1873-4162
DOI:10.1016/j.legalmed.2014.03.003