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High-resolution 3D-MRI of postmortem brain specimens fixed by formalin and gadoteridol

Highlights • Gadoteridol can infiltrate deep into the immersion-fixed brain. • MP-RAGE sequence of brain fixed by gadoteridol-mixed formalin yield a high contrast. • We achieved an acquisition high resolution image of 0.5 mm within 30 min. • MRI of fixed brain is highly compatible in forensic practi...

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Published in:	Legal medicine (Tokyo, Japan) Japan), 2014-07, Vol.16 (4), p.218-221
Main Authors:	Kanawaku, Yoshimasa, Someya, Satoka, Kobayashi, Tomoya, Hirakawa, Keiko, Shiotani, Seiji, Fukunaga, Tatsushige, Ohno, Youkichi, Kawakami, Saki, Kanetake, Jun
Format:	Article
Language:	English
Subjects:	Autopsy - methods Brain Brain - drug effects Brain - pathology Contrast Media Fixatives Forensic Pathology - methods Formaldehyde Gadolinium Gadoteridol Heterocyclic Compounds Humans Imaging, Three-Dimensional - methods Immersion Internal Medicine Magnetic resonance imaging Magnetic Resonance Imaging - methods Neuroimaging - methods Organometallic Compounds Postmortem MRI Specimen Tokyo
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container_title	Legal medicine (Tokyo, Japan)
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creator	Kanawaku, Yoshimasa Someya, Satoka Kobayashi, Tomoya Hirakawa, Keiko Shiotani, Seiji Fukunaga, Tatsushige Ohno, Youkichi Kawakami, Saki Kanetake, Jun
description	Highlights • Gadoteridol can infiltrate deep into the immersion-fixed brain. • MP-RAGE sequence of brain fixed by gadoteridol-mixed formalin yield a high contrast. • We achieved an acquisition high resolution image of 0.5 mm within 30 min. • MRI of fixed brain is highly compatible in forensic practices.
doi_str_mv	10.1016/j.legalmed.2014.03.003
format	article
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subjects	Autopsy - methods Brain Brain - drug effects Brain - pathology Contrast Media Fixatives Forensic Pathology - methods Formaldehyde Gadolinium Gadoteridol Heterocyclic Compounds Humans Imaging, Three-Dimensional - methods Immersion Internal Medicine Magnetic resonance imaging Magnetic Resonance Imaging - methods Neuroimaging - methods Organometallic Compounds Postmortem MRI Specimen Tokyo
title	High-resolution 3D-MRI of postmortem brain specimens fixed by formalin and gadoteridol
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