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Immunological identification of 1,25-dihydroxyvitamin D sub(3) receptors in human promyelocytic leukemic cells (HL-60) during homologous regulation

Immunological techniques were utilized to detect 1,25-dihydroxyvitamin D sub(3) (1,25-(OH) sub(2)D sub(3)) receptor levels and to characterize physical/chemical changes in receptors in human promyelocytic leukemic cells (HL-60) during continuous exposure to hormone. The data presented here strongly...

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Bibliographic Details
Published in:The Journal of biological chemistry 1989-01, Vol.264 (23), p.13701-13705
Main Authors: Lee, Young Sook, Inaba, M, DeLucas, H F, Mellon, W S
Format: Article
Language:English
Online Access:Get full text
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Summary:Immunological techniques were utilized to detect 1,25-dihydroxyvitamin D sub(3) (1,25-(OH) sub(2)D sub(3)) receptor levels and to characterize physical/chemical changes in receptors in human promyelocytic leukemic cells (HL-60) during continuous exposure to hormone. The data presented here strongly support the hypothesis of homologous regulation of 1,25-(OH) sub(2)D sub(3) receptors in intact human target cells.
ISSN:0021-9258