CLINICAL STUDIES ON CEFADROXIL IN THE PEDIATRICS

The present paper reports the results which were obtained in a clinical trial of cefadroxil (CDX), a new oral cephalosporin, in the pediatric field. (1) A total of 20 patients with infectious diseases including 9 urinary tract infection, 7 acute tonsillitis, 2 scarlet fever, 1 pyodermia and 1 recurr...

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Bibliographic Details
Published in:Japanese journal of antibiotics 1981/01/25, Vol.34(1), pp.25-32
Main Authors: TERASHIMA, ITARU, NAKAMURA, AKIRA, OKIMOTO, YURI, KUROSAKI, TOMOMICHI, UEHARA, SUZUKO
Format: Article
Language:Japanese
Subjects:
Adolescent
Age Factors
Bacteria - drug effects
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Cefadroxil
Cephalexin - administration & dosage
Cephalexin - adverse effects
Cephalexin - analogs & derivatives
Cephalexin - pharmacology
Child
Child, Preschool
Clinical Trials as Topic
Drug Resistance, Microbial
Female
Humans
Infant
Male
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Summary:The present paper reports the results which were obtained in a clinical trial of cefadroxil (CDX), a new oral cephalosporin, in the pediatric field. (1) A total of 20 patients with infectious diseases including 9 urinary tract infection, 7 acute tonsillitis, 2 scarlet fever, 1 pyodermia and 1 recurrent bronchitis were treated with CDX. Of the. 20 cases, the clinical response was excellent in 15 cases (75%), good in 4 cases (20%), and fair in 1 case (5%). (2) Efficacy classified by causative organisms was as follows; E. coli, 100%; S. pyogenes, 87, 5%. (3) Neither adverse reactions nor abnormal laboratory results were observed.
ISSN:0368-2781
2186-5477
DOI:10.11553/antibiotics1968b.34.25