Higher-order aberrations of anterior and posterior corneal surfaces in patients with keratectasia after LASIK

• Published in: Investigative ophthalmology & visual science 2014-06, Vol.55 (6), p.3905-3911
• Main Authors: Maeda, Naoyuki, Nakagawa, Tomoya, Kosaki, Ryo, Koh, Shizuka, Saika, Makoto, Fujikado, Takashi, Nishida, Kohji
• Format: Article
• Language: English
• Subjects: Aberrometry; Adult; Corneal Wavefront Aberration - diagnosis; Dilatation, Pathologic - diagnosis; Dilatation, Pathologic - etiology; Endothelium, Corneal - pathology; Epithelium, Corneal - pathology; Female; Humans; Imaging, Three-Dimensional; Keratoconus - diagnosis; Keratoconus - etiology; Keratomileusis, Laser In Situ; Lasers, Excimer - therapeutic use; Male; Myopia - surgery; Photography; Postoperative Complications; Retrospective Studies
• ISSN: 1552-5783; 1552-5783
• DOI: 10.1167/iovs.14-14391

We investigated higher-order aberrations (HOAs) of the anterior and posterior corneal surfaces in patients with keratectasia after LASIK. The subjects comprised four groups: 12 eyes with keratectasia after LASIK, 30 eyes following LASIK without keratectasia, 30 keratoconic eyes, and 30 normal eyes. Corneal HOAs due to the anterior and posterior corneal surfaces for 6-mm pupils (root mean square [μm]) were obtained using a Scheimpflug-based corneal tomographer and compared among the four groups. There were significant differences in total HOAs of the anterior and posterior corneal surfaces (mean ± SD) in the keratectasia (2.49 ± 1.37 and 0.83 ± 0.57), keratoconus (4.50 ± 2.57 and 1.18 ± 0.65), LASIK (0.84 ± 0.25 and 0.14 ± 0.04), and normal (0.52 ± 0.15 and 0.17 ± 0.06) groups except for between keratoconus and keratectasia at the posterior surface. Keratectasia and keratoconus showed similar coma-dominant patterns at both surfaces, and there were no significant differences in the Zernike terms between both groups except for the total HOAs and coma aberration at the anterior surface. Although flap creation and laser ablation were supposed to center on the primary line of sight in LASIK, keratectasia after LASIK showed coma-dominant HOAs at both corneal surfaces. This suggests that the cornea in keratectasia has optical properties similar to those in keratoconus.