Relation of Smoking Status to Outcomes After Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest

• Published in: The American journal of cardiology 2014-07, Vol.114 (2), p.169-174
• Main Authors: Gupta, Tanush, MD, Kolte, Dhaval, MD, PhD, Khera, Sahil, MD, Aronow, Wilbert S., MD, Palaniswamy, Chandrasekar, MD, Mujib, Marjan, MD, MPH, Jain, Diwakar, MD, Sule, Sachin, MD, Ahmed, Ali, MD, MPH, Iwai, Sei, MD, Eugenio, Paul, MD, Lessner, Seth, MD, Frishman, William H., MD, Panza, Julio A., MD, Fonarow, Gregg C., MD
• Format: Article
• Language: English
• Subjects: Aged; Cardiac arrest; Cardiac arrhythmia; Cardiopulmonary Resuscitation; Cardiovascular; Confidence Intervals; Coronary vessels; CPR; Female; Heart Arrest - epidemiology; Heart Arrest - therapy; Heart attacks; Hospital Mortality - trends; Hospitals; Humans; Incidence; Inpatients; Length of Stay - trends; Male; Middle Aged; Mortality; Odds Ratio; Prognosis; Retrospective Studies; Smoking - adverse effects; Studies; United States - epidemiology
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2014.04.021

In-hospital cardiac arrest (IHCA) is common and is associated with poor prognosis. Data on the effect of smoking on outcomes after IHCA are limited. We analyzed the Nationwide Inpatient Sample databases from 2003 to 2011 for all patients aged ≥18 years who underwent cardiopulmonary resuscitation (CPR) for IHCA to examine the differences in survival to hospital discharge and neurologic status between smokers and nonsmokers. Of the 838,464 patients with CPR for IHCA, 116,569 patients (13.9%) were smokers. Smokers were more likely to be younger, Caucasian, and male. They had a greater prevalence of dyslipidemia, coronary artery disease, hypertension, chronic pulmonary disease, obesity, and peripheral vascular disease. Atrial fibrillation, heart failure, and diabetes mellitus with complications were less prevalent in smokers. Smokers were more likely to have a primary diagnosis of acute myocardial infarction (14.8% vs 9.1%, p