S-100a sub(0) protein stimulates Ca super(2+)-induced Ca super(2+) release from isolated sarcoplasmic reticulum vesicles

S-100a sub(0) protein, the alpha alpha -isoform of the S-100 family, stimulates Ca super(2+)-induced Ca super(2+) release from terminal cisternae isolated from rat skeletal muscle cells. The stimulatory effect of S-100a sub(0) is maximal at similar to 5 mu M S-100a sub(0). The effect of the protein...

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Bibliographic Details
Published in:FEBS letters 1989-01, Vol.255 (2), p.381-384
Main Authors: Fano, G, Marsili, V, Angelella, P, Aisa, M C, Giambanco, I, Donato, R
Format: Article
Language:English
Subjects:
calcium
S-100a0 protein
sarcoplasmic reticulum
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Summary:S-100a sub(0) protein, the alpha alpha -isoform of the S-100 family, stimulates Ca super(2+)-induced Ca super(2+) release from terminal cisternae isolated from rat skeletal muscle cells. The stimulatory effect of S-100a sub(0) is maximal at similar to 5 mu M S-100a sub(0). The effect of the protein on Ca super(2+)-induced Ca super(2+) release is completely inhibited by the calcium release blocker, ruthenium red.
ISSN:0014-5793