Bordetella pertussis : Why is it still circulating?

Summary Bordetella pertussis is the causal agent of whooping cough, a highly contagious respiratory disease that is life-threatening in infants under the age of three months and may also be very severe in pregnant women and seniors. This disease can be prevented by vaccination but it remains a publi...

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Bibliographic Details
Published in:The Journal of infection 2014-01, Vol.68, p.S119-S124
Main Author: Guiso, Nicole
Format: Article
Language:English
Subjects:
Bordetella pertussis
Bordetella pertussis - immunology
Bordetella pertussis - isolation & purification
Diagnostic
Humans
Indexing in process
Infant
Infectious Disease
Pertussis Vaccine - administration & dosage
Pertussis Vaccine - immunology
Vaccine
Whooping cough
Whooping Cough - epidemiology
Whooping Cough - prevention & control
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Summary:Summary Bordetella pertussis is the causal agent of whooping cough, a highly contagious respiratory disease that is life-threatening in infants under the age of three months and may also be very severe in pregnant women and seniors. This disease can be prevented by vaccination but it remains a public health problem in many developed and developing countries. So, why is B. pertussis still circulating? We need to consider several aspects of this vaccine-preventable disease when answering this question: (i) the history of the disease and the historical context in which the vaccine was developed; (ii) the type of vaccine used; (iii) the vaccination strategy and coverage; (iv) the disease surveillance after the introduction of generalized vaccination and (v) the surveillance for the causal agent of the disease.
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2013.09.022