Are we missing opportunities to confirm the diagnosis of tuberculosis by microbial culture?

Summary Setting Tuberculosis (TB) incidence is rising globally, with drug resistance becoming increasingly problematic. Microbiological confirmation ensures correct anti-tuberculous chemotherapy. Objective/design We retrospectively analysed all TB cases diagnosed in Central Manchester in 2009 invest...

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Bibliographic Details
Published in:Respiratory medicine 2013-12, Vol.107 (12), p.2022-2028
Main Authors: Al-Nakeeb, Zaid, Gupta, Vandana, Bell, Christine, Woodhead, Mark
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Aged
Bacteriological Techniques - methods
Child
Child, Preschool
Diagnostic Errors
Drug resistance
Histology
Humans
Infant
Investigation
Microbiological diagnosis
Middle Aged
Mortality
Mycobacteria
Mycobacterium
Pulmonary/Respiratory
Retrospective Studies
Studies
Tuberculosis
Tuberculosis - diagnosis
Young Adult
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Summary:Summary Setting Tuberculosis (TB) incidence is rising globally, with drug resistance becoming increasingly problematic. Microbiological confirmation ensures correct anti-tuberculous chemotherapy. Objective/design We retrospectively analysed all TB cases diagnosed in Central Manchester in 2009 investigating how often we are not achieving microbiological diagnosis, factors influencing this and whether opportunities to obtain microbiological samples are missed. Results 128/156 (82%) cases had samples sent for microbiology. Factors affecting this included disease site, with ocular disease least likely to be sampled ( p  
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2013.09.016