Biospeckle in the human sclera and impact on laser speckle correlation measurement of eye tremor

Ocular microtremor (OMT) is an involuntary fixational eye movement. We identify the implications of biospeckle for a noninvasive, laser speckle correlation technique to measure OMT. Biospeckle from the in-vivo eye is characterized and, using the resulting characteristics, a mathematical model to des...

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Bibliographic Details
Published in:Journal of biomedical optics 2013-09, Vol.18 (9), p.097009-097009
Main Authors: Kenny, Emer, Coakley, Davis, Boyle, Gerard
Format: Article
Language:English
Subjects:
Correlation analysis
Eye movements
Human
Lasers
Mathematical models
Stability
Temporal logic
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Summary:Ocular microtremor (OMT) is an involuntary fixational eye movement. We identify the implications of biospeckle for a noninvasive, laser speckle correlation technique to measure OMT. Biospeckle from the in-vivo eye is characterized and, using the resulting characteristics, a mathematical model to describe the biospeckle from the eye is designed and tested. Through in-vivo measurements, biospeckle is shown to disrupt the temporal stability of the speckle images over time. However, provided each speckle image is cross correlated with the previous image within a sufficiently short time, the stability of speckle images captured from the eye is shown to be adequate to measure OMT-like displacements.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.JBO.18.9.097009