Affective temperaments and antidepressant response in the clinical management of mood disorders

Abstract Background The aim of this study was to investigate the presence of a relationship between affective temperament and antidepressant treatment response in mood disorder patients. Methods The lifetime history of antidepressant response of 90 bipolar disorder patients and 88 major depressive d...

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Bibliographic Details
Published in:Journal of affective disorders 2014-02, Vol.155, p.138-141
Main Authors: de Aguiar Ferreira, Alexandre, Vasconcelos, Alina Gomide, Neves, Fernando Silva, Correa, Humberto
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Affect
Affective disorders
Affective temperament
Antidepressant drugs
Antidepressant response
Antidepressive Agents - therapeutic use
Biological and medical sciences
Bipolar affective disorder
Bipolar Disorder - drug therapy
Bipolar Disorder - psychology
Brazil
Depression
Depressive Disorder, Major - drug therapy
Depressive Disorder, Major - psychology
Female
Humans
Male
Mania
Medical sciences
Middle Aged
Miscellaneous
Mood disorders
Neuropharmacology
Pharmacology. Drug treatments
Psychiatry
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
Retrospective Studies
Temperament
TEMPS-A
TEMPS-Rio de Janeiro
Treatment Outcome
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Summary:Abstract Background The aim of this study was to investigate the presence of a relationship between affective temperament and antidepressant treatment response in mood disorder patients. Methods The lifetime history of antidepressant response of 90 bipolar disorder patients and 88 major depressive disorder patients were retrospectively evaluated and then assigned to one of four subgroups: complete response (CR), partial response (PR), no response (NR), and antidepressant associated mania response (AAMR). Using TEMPS-Rio de Janeiro – the brief Brazilian version of TEMPS-A – we compared affective temperament subscale scores across these groups. Results We observed a statistically significant relationship between depressive and anxious affective temperaments and no antidepressant response. In bipolar disorder patients, cyclothymic temperament ( p
ISSN:0165-0327
1573-2517
DOI:10.1016/j.jad.2013.10.038