BCG multifocal osteomyelitis. A case report

Multifocal osteomyelitis is a rare complication of the Bacille Calmette-Guerin (BCG) vaccine. It particularly affects immunocompromised children and poses a difficult diagnostic problem. A 6-month-old boy had BCG vaccination postnatally and developed extensive disseminated skeletal osteomyelitis. He...

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Bibliographic Details
Published in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2014-07, Vol.21 (7), p.761-764
Main Authors: Ben Ghozlen, H, Jerbi, M, Zitoun, Y, Abid, F, Bousoffara, R, Sassi, N
Format: Article
Language:fre
Subjects:
BCG Vaccine - adverse effects
Fatal Outcome
Humans
Infant
Male
Osteomyelitis - diagnostic imaging
Osteomyelitis - etiology
Radiography
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Summary:Multifocal osteomyelitis is a rare complication of the Bacille Calmette-Guerin (BCG) vaccine. It particularly affects immunocompromised children and poses a difficult diagnostic problem. A 6-month-old boy had BCG vaccination postnatally and developed extensive disseminated skeletal osteomyelitis. He was found to have severe combined immunodeficiency. Despite antibiotic therapy and bone marrow grafting, the disease was fatal.
ISSN:1769-664X
DOI:10.1016/j.arcped.2014.04.020