Recent advances in newborn MRI

• Published in: Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2014-07, Vol.21 (7), p.801-808
• Main Authors: Morel, B, Hornoy, P, Husson, B, Bloch, I, Adamsbaum, C
• Format: Article
• Language: fre
• Subjects: Brain - growth & development; Brain - pathology; Brain Diseases - diagnosis; Humans; Infant, Newborn; Infant, Premature; Magnetic Resonance Imaging - methods; Magnetic Resonance Imaging - trends
• ISSN: 1769-664X
• DOI: 10.1016/j.arcped.2014.04.001

The accurate morphological exploration of the brain is a major challenge in neonatology that advances in magnetic resonance imaging (MRI) can now provide. MRI is the gold standard if an hypoxic ischemic pathology is suspected in a full term neonate. In prematures, the specific role of MRI remains to be defined, secondary to US in any case. We present a state of the art of hardware and software technical developments in MRI. The increase in magnetic field strength (3 tesla) and the emergence of new MRI sequences provide access to new information. They both have positive and negative consequences on the daily clinical data acquisition use. The semiology of brain imaging in full term newborns and prematures is more extensive and complex and thereby more difficult to interpret. The segmentation of different brain structures in the newborn, even very premature, is now available. It is now possible to dissociate the cortex and basal ganglia from the cerebral white matter, to calculate the volume of anatomical structures, which improves the morphometric quantification and the understanding of the normal and abnormal brain development. MRI is a powerful tool to analyze the neonatal brain. The relevance of the diagnostic contribution requires an adaptation of the parameters of the sequences to acquire and of the image processing methods.