The influence of compliant boundary proximity on the fundamental and subharmonic emissions from individual microbubbles

The proximity of a solid-liquid boundary has been theoretically predicted to affect nonlinear microbubble emissions, but to date there has been no experimental validation of this effect. In this study, individual microbubbles (n = 15) were insonicated at f = 11 MHz as a function of offset distance f...

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Bibliographic Details
Published in:The Journal of the Acoustical Society of America 2014-07, Vol.136 (1), p.EL40-EL46
Main Authors: Helfield, Brandon L, Leung, Ben Y C, Goertz, David E
Format: Article
Language:English
Subjects:
Acoustics
Computer Simulation
Elasticity
Microbubbles
Motion
Nonlinear Dynamics
Numerical Analysis, Computer-Assisted
Scattering, Radiation
Sound
Surface Tension
Viscosity
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Summary:The proximity of a solid-liquid boundary has been theoretically predicted to affect nonlinear microbubble emissions, but to date there has been no experimental validation of this effect. In this study, individual microbubbles (n = 15) were insonicated at f = 11 MHz as a function of offset distance from a compliant (agarose) planar boundary by employing an optical trapping apparatus. It was found that fundamental scattering increases while subharmonic scattering decreases as the microbubble approaches the boundary. Although a microbubble-boundary model can predict the qualitative trends observed for a subset of encapsulation properties, further modeling efforts are required to completely model compliant boundary-microbubble interactions.
ISSN:0001-4966
1520-8524
DOI:10.1121/1.4885544