ANAPLASTIC MANDIBULAR CARCINOMA IN A MEERKAT (SURICATA SURICATTA)

An 8-yr-old female slender-tailed meerkat (Suricata suricatta) presented with a necrotic sublingual mass and osteolysis of the mandible. After 1 mo of palliative care, the meerkat was euthanized. The mass was diagnosed histologically as an anaplastic carcinoma with extensive rostral mandibular destr...

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Bibliographic Details
Published in:Journal of zoo and wildlife medicine 2014-06, Vol.45 (2), p.413-416
Main Authors: Dadone, Liza I, Garner, Michael M, Klaphake, Eric, Johnston, Matthew S, Han, Sushan
Format: Article
Language:English
Subjects:
Anaplastic carcinoma
Animals
Brief Communication
BRIEF COMMUNICATIONS
Canines
Carcinoma - pathology
Carcinoma - veterinary
Chromogranins
Epithelial cells
Female
Herpestidae
Jaw Neoplasms - pathology
Jaw Neoplasms - veterinary
Mandible
meerkat
Melanin
Neoplasia
oral
Squamous cell carcinoma
Suricata suricatta
Tumors
Vimentin
Zoos
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Summary:An 8-yr-old female slender-tailed meerkat (Suricata suricatta) presented with a necrotic sublingual mass and osteolysis of the mandible. After 1 mo of palliative care, the meerkat was euthanized. The mass was diagnosed histologically as an anaplastic carcinoma with extensive rostral mandibular destruction. Immunohistochemistry for vimentin and cytokeratin was validated in this nontypical species and showed that neoplastic cells expressed both mesenchymal and epithelial characteristics, suggestive of a primitive and poorly differentiated tumor. A review of 150 adult slender-tailed meerkat histopathology reports showed a 2% prevalence of orofacial neoplasia, suggesting that oral neoplasms are uncommon in meerkats.
ISSN:1042-7260
1937-2825
DOI:10.1638/2013-0158R.1