Dose per unit cumulated activity (S-values) for e super(-) and beta emitting radionuclides in cancer cell models calculated by Monte Carlo simulation

Cell dosimetry is relevant regarding new efforts in specific molecular radiotherapy using Auger, CE and beta emitters. Absorbed dose in cells can be obtained by means of the dose per unit cumulated activity (S-values), together with the activity distribution. In this work, Monte Carlo simulation cod...

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Bibliographic Details
Published in:Applied radiation and isotopes 2014-08, Vol.90, p.229-233
Main Authors: Rojas-Calderon, EL, Torres-Garcia, E, Avila, O
Format: Article
Language:English
Online Access:Get full text
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Summary:Cell dosimetry is relevant regarding new efforts in specific molecular radiotherapy using Auger, CE and beta emitters. Absorbed dose in cells can be obtained by means of the dose per unit cumulated activity (S-values), together with the activity distribution. In this work, Monte Carlo simulation codes PENELOPE and MCNPX were used to obtain cellular S-values for point and extended sources of electrons and beta emitting radionuclides in the nucleus of breast (MDA-MB231, MCF7) and prostate (PC3) cancer cell models.
ISSN:0969-8043
DOI:10.1016/j.apradiso.2014.04.012