Cerebrospinal Fluid Leaks and Their Management After Anterior Cervical Discectomy and Fusion: A Report of 13 Cases and a Review of the Literature

• Published in: Spine (Philadelphia, Pa. 1976) Pa. 1976), 2014-07, Vol.39 (16), p.E936-E943
• Main Authors: Syre, Peter, Bohman, Leif-Erik, Baltuch, Gordon, Le Roux, Peter, Welch, William C
• Format: Article
• Language: English
• Subjects: Adult; Cerebrospinal Fluid Leak - diagnosis; Cerebrospinal Fluid Leak - etiology; Cerebrospinal Fluid Leak - therapy; Cervical Vertebrae - surgery; Diskectomy - adverse effects; Female; Follow-Up Studies; Humans; Male; Middle Aged; Postoperative Complications - diagnosis; Postoperative Complications - etiology; Postoperative Complications - therapy; Retrospective Studies; Spinal Fusion - adverse effects; Treatment Outcome
• ISSN: 0362-2436; 1528-1159
• DOI: 10.1097/BRS.0000000000000404

STUDY DESIGN.Retrospective medical record review and literature review. OBJECTIVE.To identify cases where a cerebrospinal fluid (CSF) leak occurred during an anterior cervical discectomy and fusion (ACDF) and to create a management algorithm based on the findings. SUMMARY OF BACKGROUND DATA.ACDF is a commonly performed spinal operation. It is effective with very low complication rates. One rare complication of ACDF is a CSF leak. There is limited information on the management of CSF leaks after ACDF and management is on a surgeon-by-surgeon basis. METHODS.We reviewed 3 surgeonsʼ case logs and identified cases where a CSF leak was encountered during ACDF and reviewed the patientsʼ medical records, operative reports and imaging to determine how these leaks were managed. We also performed a PubMed search for articles about the presentation and management of CSF leaks after ACDF. RESULTS.Thirteen CSF leaks were identified in 1223 ACDFs, corresponding to a CSF leak rate of 1%. Of these, 9 were successfully treated with intraoperative repair. Postoperative lumbar drainage was used in the remaining 4 patients and was successful in 1 patient. Three patients underwent neck re-exploration and attempted delayed repair. Three patients, including one who was found to have hydrocephalus, ultimately required continuous CSF diversion via shunting. We identified 7 case reports of CSF leak in ADCF in the literature and 1 article that reviewed the prevalence and management of this complication. CONCLUSION.CSF leak after ACDF is an uncommon complication that can usually be repaired. We provide a stepwise management strategy for CSF leaks in ACDF.Level of Evidence5