Serial and prolonged EEG monitoring in anti- N -Methyl- d -Aspartate receptor encephalitis

Highlights • Generalized rhythmic delta activity (GRDA) is a common finding in patients with anti-NMDAR encephalitis, but may not be present on a routine 30-min EEG recording. • Serial and continuous EEG monitoring may be more adequate to detect characteristic patterns (GRDA and extreme delta brush)...

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Bibliographic Details
Published in:Clinical neurophysiology 2014-08, Vol.125 (8), p.1541-1544
Main Authors: da Silva-Júnior, Francisco Pereira, Castro, Luiz Henrique Martins, Andrade, Joaquina Queiroz, Bastos, Carla Guimarães, Moreira, Camila Hobi, Valério, Rosa Maria Figueiredo, Jorge, Carmen Lisa, Marchiori, Paulo Eurípedes, Nitrini, Ricardo, Garzon, Eliana
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anti-N-Methyl-d-Aspartate receptor
Anti-N-Methyl-D-Aspartate Receptor Encephalitis - complications
Anti-N-Methyl-D-Aspartate Receptor Encephalitis - diagnosis
Anti-N-Methyl-D-Aspartate Receptor Encephalitis - etiology
Benzodiazepines - administration & dosage
Delta Rhythm
Electroencephalography
Electroencephalography - drug effects
Electroencephalography - methods
Encephalitis
Environmental Monitoring - methods
Female
Humans
Injections, Intravenous
Neurology
Seizures - etiology
Stroke
Young Adult
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Summary:Highlights • Generalized rhythmic delta activity (GRDA) is a common finding in patients with anti-NMDAR encephalitis, but may not be present on a routine 30-min EEG recording. • Serial and continuous EEG monitoring may be more adequate to detect characteristic patterns (GRDA and extreme delta brush) and seizures in these patients. • GRDA should not be interpreted as indicative of ictal activity or nonconvulsive status, unless clear frequency, voltage or field evolution, and both electrographic and clinical response to a benzodiazepine are observed.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2014.01.001