Effect of Terminalia chebula Extract and Chlorhexidine on Salivary pH and Periodontal Health: 2 Weeks Randomized Control Trial

A double blind, randomized, controlled study with three parallel treatment groups was done to evaluate the efficacy of a Terminalia chebula 10% mouth rinse compared with chlorhexidine 0.12% mouth rinse, applied two times daily for 2 weeks, in the treatment of dental plaque and gingivitis. Seventy‐ei...

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Bibliographic Details
Published in:Phytotherapy research 2014-07, Vol.28 (7), p.992-998
Main Authors: Gupta, Devanand, Bhaskar, D. J, Gupta, Rajendra Kumar, Karim, Bushra, Gupta, Vipul, Punia, Himanshu, Batra, Manu, Jain, Ankita, Agarwal, Amit, Singh, Pradeep
Format: Article
Language:English
Subjects:
Adult
chlorhexidine
Chlorhexidine - therapeutic use
Dental Plaque - drug therapy
Dental Plaque Index
Double-Blind Method
Female
Fruit - chemistry
gingival index
gingivitis
Gingivitis - drug therapy
Humans
Hydrogen-Ion Concentration
inflammation
Male
mouth
mouthwash
Mouthwashes - therapeutic use
neutralization
patients
Periodontal Index
Plant Extracts - therapeutic use
plaque index
Saliva - chemistry
Terminalia - chemistry
Terminalia chebula
therapeutics
Treatment Outcome
Young Adult
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Summary:A double blind, randomized, controlled study with three parallel treatment groups was done to evaluate the efficacy of a Terminalia chebula 10% mouth rinse compared with chlorhexidine 0.12% mouth rinse, applied two times daily for 2 weeks, in the treatment of dental plaque and gingivitis. Seventy‐eight patients were included in the study. The efficacy variables were periodontal indices on days 0, 7 and 14 after commencement of therapy. Twenty six patients received chlorhexidine mouth rinse, twenty six Terminalia chebula mouth rinse and twenty six received saline solution. The clinical parameters were significantly reduced by both chlorhexidine and Terminalia chebula mouth rinse although no significant difference was seen between the two groups (P > 0.05). This study demonstrated that Terminalia chebula mouth rinse is effective in reducing microbial plaque, gingival inflammation and neutralizing salivary pH. Copyright © 2013 John Wiley & Sons, Ltd.
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.5075