An in silico model to predict the potential of dietary proteins as sources of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides

An in silico approach was developed to predict the potential of 72 dietary proteins to act as a source of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides. The model takes 68 DPP-IV inhibitory peptides (having an IC50 value

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Bibliographic Details
Published in:Food chemistry 2014-12, Vol.165, p.489-498
Main Authors: NONGONIERMA, Alice B, FITZGERALD, Richard J
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Caseins - chemistry
Cattle
Computer Simulation
Diabetes. Impaired glucose tolerance
Dipeptidyl Peptidase 4 - chemistry
Dipeptidyl-Peptidase IV Inhibitors - chemistry
Dipeptidyl-Peptidase IV Inhibitors - isolation & purification
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Food toxicology
Lactalbumin - chemistry
Medical sciences
Peptides - chemistry
Peptides - isolation & purification
Toxicology
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Description
Summary:An in silico approach was developed to predict the potential of 72 dietary proteins to act as a source of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides. The model takes 68 DPP-IV inhibitory peptides (having an IC50 value
ISSN:0308-8146
1873-7072
DOI:10.1016/j.foodchem.2014.05.090