High diagnostic accuracy and reproducibility of fine-needle aspiration cytology for diagnosing salivary gland tumors: cytohistologic correlation in 182 cases

Objective The purpose of this study was to assess the efficacy and reproducibility of the cytologic diagnosis of salivary gland tumors (SGTs) using fine-needle aspiration cytology (FNAC). The study aimed to determine diagnostic accuracy, sensitivity, and specificity and to evaluate the extent of int...

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Published in:Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2014-08, Vol.118 (2), p.226-235
Main Authors: Díaz, Katya Pulido, DDS, MSc, Gerhard, Renê, MD, PhD, Domingues, Regina Barros, MD, Martins, Leandro Liporoni, MD, Prado Ribeiro, Ana Carolina, DDS, PhD, Lopes, Márcio Ajudarte, DDS, PhD, Carneiro, Paulo Campos, MD, PhD, Vargas, Pablo Agustin, DDS, PhD, FRCPath
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biopsy, Fine-Needle
Cytodiagnosis
Dentistry
Female
Humans
Male
Middle Aged
Neoplasm Staging
Predictive Value of Tests
Reproducibility of Results
Salivary Gland Neoplasms - pathology
Sensitivity and Specificity
Surgery
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Summary:Objective The purpose of this study was to assess the efficacy and reproducibility of the cytologic diagnosis of salivary gland tumors (SGTs) using fine-needle aspiration cytology (FNAC). The study aimed to determine diagnostic accuracy, sensitivity, and specificity and to evaluate the extent of interobserver agreement. Study Design We retrospectively evaluated SGTs from the files of the Division of Pathology at the Clinics Hospital of São Paulo and Piracicaba Dental School between 2000 and 2006. Results We performed cytohistologic correlation in 182 SGTs. The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were 94%, 100%, 100%, 100%, and 99%, respectively. The interobserver cytologic reproducibility showed significant statistical concordance ( P  
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2014.04.004