INHIBITORY EFFECT OF GYMNEMA SYLVESTRE, STEVIA REBAUDIANA, PHYLLANTHUS EMBLICA AND SYZYGIUM CUMINI ON PORCINE PANCREATIC AMYLASE

Diabetes has become a common global health problem that affects >170 million people worldwide. It is one of the leading causes of death and disability. It is estimated that by 2030, the number will rise to 366 million. The majority of diabetes is type 2 diabetes (T2D) caused by a combination of i...

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Bibliographic Details
Published in:Global journal of research on medicinal plants and indigenous medicine 2013-08, Vol.2 (8), p.554-554
Main Authors: Dayananda, K S, Gopinath, S M, Murthy, R K
Format: Article
Language:English
Subjects:
Asian people
Ayurvedic medicine
Diabetes
Enzymes
Free radicals
Herbal medicine
Insulin
Lipids
Mortality
Oxidative stress
Phyllanthus emblica
Polyphenols
Proteins
Stevia rebaudiana
Studies
Syzygium cumini
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Summary:Diabetes has become a common global health problem that affects >170 million people worldwide. It is one of the leading causes of death and disability. It is estimated that by 2030, the number will rise to 366 million. The majority of diabetes is type 2 diabetes (T2D) caused by a combination of impaired insulin secretion from pancreatic beta cells and insulin resistance of the peripheral target tissues, especially muscle and liver. The 'top' three countries in terms of the number of T2D individuals with diabetes are India, China; and the US. Clearly, T2D has become an epidemic in the 21st century where India leads the world with the largest number of diabetic subjects. In this study, the inhibitory effect of Syzygium cumini, Gymnema sylvestre, Stevia rebaudiana and Phyllanthus emblica extract on porcine pancreatic amylase. The most significant inhibitory activity was obtained with the aqueous and ethanolic extracts of Gymnema sylvestre and Syzygium cumini.
ISSN:2277-4289