Outcomes and predictors of microvascular invasion of solitary hepatocellular carcinoma

Aim Microvascular invasion (MVI) is an important risk factor for early recurrence of hepatocellular carcinoma (HCC), but preoperative prediction of MVI is difficult. Methods A retrospective review was undertaken on 167 patients with primary solitary HCC who underwent initial hepatectomy. Independent...

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Bibliographic Details
Published in:Hepatology research 2014-08, Vol.44 (8), p.846-853
Main Authors: Hirokawa, Fumitoshi, Hayashi, Michihiro, Miyamoto, Yoshiharu, Asakuma, Mitsuhiro, Shimizu, Tetsunosuke, Komeda, Koji, Inoue, Yoshihiro, Uchiyama, Kazuhisa
Format: Article
Language:English
Subjects:
AFP-L3
HCC
microvascular invasion
PIVKA-II
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Summary:Aim Microvascular invasion (MVI) is an important risk factor for early recurrence of hepatocellular carcinoma (HCC), but preoperative prediction of MVI is difficult. Methods A retrospective review was undertaken on 167 patients with primary solitary HCC who underwent initial hepatectomy. Independent predictors of MVI were identified, and factors affecting disease‐free survival in patients with MVI were clarified. Results Of the 167 patients, 20 patients (12%) had MVI. Recurrence rates of HCC after hepatectomy in MVI patients were significantly worse than in patients without MVI (P 
ISSN:1386-6346
1872-034X
DOI:10.1111/hepr.12196