Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing

Non-contact thermometry is essential in biomedical studies requiring thermal sensing and imaging with high thermal and spatial resolutions. In this work, we report the potential use of Er:Yb:NaYF4 and Er:Yb:NaY2F5O up-conversion nanoparticles as thermal sensors by means of lifetime based luminescent...

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Bibliographic Details
Published in:Nanoscale 2014-08, Vol.6 (16), p.9727-9733
Main Authors: Savchuk, Ol A, Haro-González, P, Carvajal, J J, Jaque, D, Massons, J, Aguiló, M, Díaz, F
Format: Article
Language:English
Subjects:
Fluorescent Dyes - chemistry
Fluorides - chemistry
Metal Nanoparticles - chemistry
Metals, Rare Earth - chemistry
Particle Size
Temperature
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Summary:Non-contact thermometry is essential in biomedical studies requiring thermal sensing and imaging with high thermal and spatial resolutions. In this work, we report the potential use of Er:Yb:NaYF4 and Er:Yb:NaY2F5O up-conversion nanoparticles as thermal sensors by means of lifetime based luminescent thermometry. We demonstrate how Er:Yb:NaY2F5O nanocrystals present a higher thermal sensitivity than the Er:Yb:NaYF4 ones and that their lifetime thermal coefficient is comparable to those corresponding to other nano-sized luminescent systems already used for high resolution lifetime fluorescence thermal sensing. We evaluate the potential use of Er:Yb:NaY2F5O nanoparticles as lifetime based thermal probes by providing the first experimental evidence on sub-tissue lifetime fluorescence thermal sensing by using up-conversion nanoparticles in an ex vivo experiment.
ISSN:2040-3372
DOI:10.1039/c4nr02305f