Multiple Repeat Prostate Biopsies and the Detection of Clinically Insignificant Cancer in Men With Large Prostates

Objective To determine the impact of repeating prostate biopsies on the risk of detecting clinically insignificant prostate cancer (PCa) in larger prostate glands. Methods We performed a retrospective cohort study using patients enrolled in our institutional PCa registry from 1991 to 2008 to assess...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2014-08, Vol.84 (2), p.380-385
Main Authors: Pietzak, Eugene J, Resnick, Matthew J, Mucksavage, Philip, Van Arsdalen, Keith, Wein, Alan J, Malkowicz, S. Bruce, Guzzo, Thomas J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle - statistics & numerical data
Cohort Studies
Humans
Male
Medical sciences
Middle Aged
Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
Nephrology. Urinary tract diseases
Prostate - pathology
Prostatic Neoplasms - pathology
Retrospective Studies
Risk Factors
Tumors
Urology
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Summary:Objective To determine the impact of repeating prostate biopsies on the risk of detecting clinically insignificant prostate cancer (PCa) in larger prostate glands. Methods We performed a retrospective cohort study using patients enrolled in our institutional PCa registry from 1991 to 2008 to assess the association of prostate volume and clinically insignificant PCa in men undergoing multiple prostate biopsies. Patients were stratified by prostate volume into 2 cohorts (
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2014.04.029