Macrotroponin Causing Elevation in Cardiac Troponin I

Abstract We report a case of macrotroponin causing persistently raised levels of cardiac troponin I (cTnI) in a 57-year-old man with recurrent atypical chest pain. Macrotroponin, a troponin-immunoglobulin complex, should be considered when cTnI values are inconsistent with the clinical picture, and...

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Bibliographic Details
Published in:Canadian journal of cardiology 2014-08, Vol.30 (8), p.956.e5-956.e6
Main Authors: Wong, Sophia L., MD, Isserow, Saul, MBBCh, FRCPC, Pudek, Morris, PhD, FACB
Format: Article
Language:English
Subjects:
Autoantibodies - blood
Cardiovascular
Chest Pain - etiology
Humans
Immunoglobulin G - immunology
Male
Middle Aged
Troponin I - blood
Troponin I - immunology
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Summary:Abstract We report a case of macrotroponin causing persistently raised levels of cardiac troponin I (cTnI) in a 57-year-old man with recurrent atypical chest pain. Macrotroponin, a troponin-immunoglobulin complex, should be considered when cTnI values are inconsistent with the clinical picture, and fail to demonstrate a rise and/or fall pattern in suspected cases of acute coronary syndrome. Clear and effective communication between cardiologists and laboratorians is essential in the management of patients with macrotroponin.
ISSN:0828-282X
1916-7075
DOI:10.1016/j.cjca.2014.03.037