Hepatic angiomyolipoma: what management?

An 80-year-old woman was referred for the surgical treatment of a 110-mm right hepatic tumor. The biopsy revealed an adenoma, and a right hepatectomy was performed. Histopathology indicated a major fat component with epitheliod cells, immunoreactivity for HMB45, Melan A, and smooth muscle actin, des...

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Bibliographic Details
Published in:Acta chirurgica belgica 2014-03, Vol.114 (2), p.139-142
Main Authors: Barbier, L, Torrents, J, Hardwigsen, J
Format: Article
Language:English
Subjects:
Adenoma - diagnosis
Aged, 80 and over
Angiomyolipoma - diagnosis
Angiomyolipoma - surgery
Diagnostic Errors
Female
Hepatectomy
Humans
Liver Neoplasms - diagnosis
Liver Neoplasms - surgery
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Summary:An 80-year-old woman was referred for the surgical treatment of a 110-mm right hepatic tumor. The biopsy revealed an adenoma, and a right hepatectomy was performed. Histopathology indicated a major fat component with epitheliod cells, immunoreactivity for HMB45, Melan A, and smooth muscle actin, describing a hepatic epithelioid angiomyolipoma (AML). The AML belongs to the group of tumors with a Perivascular Epithelioid Cell differentiation. Its diagnosis is based on imaging and biopsy, and therefore might be difficult. Hepatic AML are mainly benign tumors; however, some tend to behave in a malignant manner. In case of histological proof, close clinical and radiological monitoring can be proposed if its size is less than 5 cm and no pejorative histological features are found. Nevertheless, follow-up is still required if resection is performed in search of recurrence or metastatic spread.
ISSN:0001-5458
DOI:10.1080/00015458.2014.11680997