Comparison of Long-Term Mortality After Acute Myocardial Infarction Treated by Percutaneous Coronary Intervention in Patients Living Alone Versus Not Living Alone at the Time of Hospitalization

• Published in: The American journal of cardiology 2014-08, Vol.114 (4), p.522-527
• Main Authors: Nakatsuma, Kenji, MD, Shiomi, Hiroki, MD, Watanabe, Hiroki, MD, Morimoto, Takeshi, MD, PhD, Taniguchi, Tomohiko, MD, Toyota, Toshiaki, MD, Furukawa, Yutaka, MD, Nakagawa, Yoshihisa, MD, Horie, Minoru, MD, Kimura, Takeshi, MD
• Format: Article
• Language: English
• Subjects: Aged; Cardiovascular; Cause of Death - trends; Clinical outcomes; Coronary Angiography; Coronary vessels; Female; Follow-Up Studies; Heart attacks; Hospital Mortality - trends; Hospitalization; Hospitalization - statistics & numerical data; Humans; Japan - epidemiology; Male; Mortality; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - mortality; Myocardial Infarction - surgery; Percutaneous Coronary Intervention; Registries; Retrospective Studies; Risk Factors; Survival Rate - trends; Time Factors; Treatment Outcome
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2014.05.029

Living alone was reported to be associated with increased risk of cardiovascular disease. There are, however, limited data on the relation between living alone and all-cause mortality in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). The Coronary REvascularization Demonstrating Outcome Study in Kyoto (CREDO-Kyoto) AMI registry was a cohort study of patients with AMI enrolled in 26 hospitals in Japan from 2005 through 2007. For the current analysis, we included those patients who underwent PCI within 24 hours of symptom onset, and we assessed their living status to determine if living alone would be an independent prognostic risk factor. Among 4,109 patients eligible for the current analysis of 5,429 patients enrolled in the CREDO-Kyoto AMI registry, 515 patients (12.5%) were living alone at the time of hospital admission. The cumulative 5-year incidence of all-cause death was 18.3% in the living alone group and 20.1% in the not living alone group (log-rank p = 0.77). After adjusting for potential confounders, risk of the living alone group relative to the not living alone group for all-cause death was not significantly different (adjusted hazard ratio 0.82, 95% confidence interval 0.65 to 1.02, p = 0.08). In a subgroup analysis stratified by age, the adjusted risk for all-cause death was also not different between the living alone group and the not living alone group both in the older population (aged ≥75 years) and the younger population (aged