The role of prenatal, perinatal and postnatal factors in the explanation of socioeconomic inequalities in preschool asthma symptoms: the Generation R Study

Background The authors assessed whether socioeconomic inequalities in asthma symptoms were already present in preschool children and to what extent prenatal, perinatal and postnatal risk factors for asthma symptoms mediate the effect of socioeconomic status (SES). Methods The study included 3136 Dut...

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Bibliographic Details
Published in:Journal of epidemiology and community health (1979) 2012-11, Vol.66 (11), p.1017-1024
Main Authors: Hafkamp-de Groen, Esther, van Rossem, Lenie, de Jongste, Johan C, Mohangoo, Ashna D, Moll, Henriëtte A, Jaddoe, Vincent W V, Hofman, Albert, Mackenbach, Johan P, Raat, Hein
Format: Article
Language:English
Subjects:
Adult
Age
Asthma
Asthma - epidemiology
Asthma - etiology
asthma symptoms
Biological and medical sciences
birth defects
Breastfeeding & lactation
Child and Adolescent Health
child health
Child, Preschool
Childhood
Children
Children & youth
Chronic obstructive pulmonary disease, asthma
Educational levels
Ethnicity
Families & family life
Family income
Female
General aspects
health expectancy
Health risks
Hospitals
Household income
Humans
infant mortality
Logistic Models
Male
maternal educational level
Medical sciences
Miscellaneous
Netherlands - epidemiology
Odds Ratio
Parents & parenting
Perinatal Care
perinatal epidemiology
Pneumology
Postnatal Care
Pregnancy
Prenatal Care
Prenatal Exposure Delayed Effects
Preschool children
Preschool education
Prevalence
preventive medicine
Prospective Studies
Public health
Public health. Hygiene
Public health. Hygiene-occupational medicine
Questionnaires
R&D
Research & development
Respiratory Sounds - etiology
Risk Factors
Social Environment
social epidemiology
social inequalities
Socioeconomic Factors
Socioeconomic status
Socioeconomics
Studies
Surveys and Questionnaires
Symptoms
Wheezing
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Summary:Background The authors assessed whether socioeconomic inequalities in asthma symptoms were already present in preschool children and to what extent prenatal, perinatal and postnatal risk factors for asthma symptoms mediate the effect of socioeconomic status (SES). Methods The study included 3136 Dutch children participating in the Generation R Study, a prospective cohort study. Adjusted ORs of asthma symptoms for low and middle SES (household income and maternal education) compared to high SES were calculated after adjustment for potential confounders and also adjusted for prenatal, perinatal and postnatal mediators at preschool age. Results At age 1 year, low-SES children had a 40% lower risk of asthma symptoms compared to high-SES children (p
ISSN:0143-005X
1470-2738
DOI:10.1136/jech-2011-200333