Prognostic analytes in dogs with Leishmania infantum infection living in a non-endemic area

Due to increasing numbers of dogs that are imported from, or have been visiting Mediterranean countries, canine leishmaniasis has become a very important infectious disease in Germany. The aim of this study was to determine which laboratory and clinical parameters can be used as prognostic factors,...

Full description

Saved in:
Bibliographic Details
Published in:Veterinary record 2012-10, Vol.171 (16), p.399-399
Main Authors: Geisweid, K., Mueller, R., Sauter-Louis, C., Hartmann, K.
Format: Article
Language:English
Subjects:
Anemia
Animals
Antibodies
Antibodies, Protozoan - blood
Antiprotozoal Agents - therapeutic use
Cellular biology
Dog Diseases - diagnosis
Dog Diseases - drug therapy
Dog Diseases - mortality
Dogs
Female
Germany - epidemiology
Hematology
Infections
Laboratories
Leishmania infantum
Leishmania infantum - immunology
Leishmaniasis, Visceral - diagnosis
Leishmaniasis, Visceral - drug therapy
Leishmaniasis, Visceral - mortality
Leishmaniasis, Visceral - veterinary
Male
Medical prognosis
Medical records
Mediterranean Region
Parasites
Parasitic diseases
Patients
Prognosis
Questionnaires
Retrospective Studies
Risk Factors
Statistical analysis
Survival Analysis
Thrombocytopenia
Travel
Urine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Due to increasing numbers of dogs that are imported from, or have been visiting Mediterranean countries, canine leishmaniasis has become a very important infectious disease in Germany. The aim of this study was to determine which laboratory and clinical parameters can be used as prognostic factors, whether level of antibody titre is a prognostic factor, and whether treatment leads to a better prognosis in a country in which reinfection is extremely unlikely. Data of 72 dogs infected with Leishmania infantum that had been presented to the Clinic of Small Animal Medicine of the LMU University of Munich, Germany, and whose owners answered a detailed questionnaire, were reviewed retrospectively. All dogs included in the study had clinical signs compatible with canine leishmaniasis. No correlation between the level of antibody titres (carried out by immunofluorescence assay) and survival time was found (p = 0.982). However, there was a significant correlation between survival time and presence of proteinuria (p 
ISSN:0042-4900
2042-7670
2042-7670
DOI:10.1136/vr.100637