A Meta-analysis of 2-Year Effect After Surgery: Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity and Diabetes Mellitus

• Published in: Obesity surgery 2014-09, Vol.24 (9), p.1528-1535
• Main Authors: Zhang, Chengda, Yuan, Yuan, Qiu, Cuiqiong, Zhang, Weidong
• Format: Article
• Language: English
• Subjects: Body Mass Index; Comparative studies; Diabetes; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - surgery; Gastrectomy; Gastric Bypass; Gastrointestinal surgery; Humans; Laparoscopy; Longitudinal Studies; Medicine; Medicine & Public Health; Meta-analysis; Obesity; Obesity, Morbid - complications; Obesity, Morbid - surgery; Postoperative Period; Review Article; Surgery; Surgical techniques; Treatment Outcome; Weight Loss
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-014-1303-1

Literature search was performed for bariatric surgery from inception to September 2013, in which the effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) on body mass index (BMI), percentage of excess weight loss (EWL%), and diabetes mellitus (DM) were compared 2 years post-surgery. A total of 9,756 cases of bariatric surgery from 16 studies were analyzed. Patients receiving LRYGB had significantly lower BMI and higher EWL% compared with those receiving LSG (BMI mean difference (MD) = −1.38, 95 % confidence interval (CI) = −1.72 to −1.03; EWL% MD = 5.06, 95 % CI = 0.24 to 9.89). Improvement rate of DM was of no difference between the two types of bariatric surgeries (RR = 1.05, 95 % CI = 0.90 to 1.23). LRYGB had better long-term effect on body weight, while both LRYGB and LSG showed similar effects on DM.