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Mean Platelet Volume is Elevated in Patients With Low High-Density Lipoprotein Cholesterol

A low high-density lipoprotein cholesterol (HDL-C) level is a predictor of increased cardiovascular risk. We assessed the mean platelet volume (MPV) in patients with low HDL-C. We studied 59 patients with low HDL-C (HDL-C ≤35 mg/dL) and 56 control participants (HDL-C levels >35 mg/dL) with simila...

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Published in:	Angiology 2014-09, Vol.65 (8), p.733-736
Main Authors:	Varol, Ercan, Aksoy, Fatih, Bas, Hasan Aydin, Ari, Hatem, Ozaydin, Mehmet
Format:	Article
Language:	English
Subjects:	Adult Aged Cholesterol, HDL - blood Cholesterol, LDL - blood Female Humans Male Mean Platelet Volume Middle Aged Platelet Activation - physiology Platelet Count Predictive Value of Tests Risk Factors
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creator	Varol, Ercan Aksoy, Fatih Bas, Hasan Aydin Ari, Hatem Ozaydin, Mehmet
description	A low high-density lipoprotein cholesterol (HDL-C) level is a predictor of increased cardiovascular risk. We assessed the mean platelet volume (MPV) in patients with low HDL-C. We studied 59 patients with low HDL-C (HDL-C ≤35 mg/dL) and 56 control participants (HDL-C levels >35 mg/dL) with similar cardiovascular risk factors. As expected, HDL-C was significantly lower among the patients with low HDL-C than that of the control group (32 ± 3 vs 51 ± 5 mg/dL, respectively; P < .001). Platelet count was significantly lower among the patients with low HDL-C than that of the control group (213 ± 60 vs 285 ± 75 × 109/L, respectively; P < .001). The MPV was significantly higher among the patients with low HDL-C than that of the control group (8.7 ± 0.6 vs 7.1 ± 0.5 fL, respectively; P < .001). We have shown that MPV was significantly elevated in patients with low HDL-C compared with control participants.
doi_str_mv	10.1177/0003319713504024
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subjects	Adult Aged Cholesterol, HDL - blood Cholesterol, LDL - blood Female Humans Male Mean Platelet Volume Middle Aged Platelet Activation - physiology Platelet Count Predictive Value of Tests Risk Factors
title	Mean Platelet Volume is Elevated in Patients With Low High-Density Lipoprotein Cholesterol
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