Recent developments in gold(i) coordination chemistry: luminescence properties and bioimaging opportunities

The fascinating biological activity of gold coordination compounds has led to the development of a wide range of complexes. The precise biological action of such species is often poorly understood and the ability to map gold distribution in cellular environments is key. This article discusses the re...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2014-09, Vol.5 (72), p.1343-1354
Main Authors: Langdon-Jones, Emily E, Pope, Simon J. A
Format: Article
Language:English
Subjects:
Animals
Auranofin - chemistry
Auranofin - toxicity
Biological activity
Cell Line, Tumor
Cell Proliferation - drug effects
Coordination Complexes - chemistry
Coordination Complexes - toxicity
Coordination compounds
Crystallography, X-Ray
Gold
Gold - chemistry
Heterocyclic Compounds - chemistry
Humans
Luminescence
Medical imaging
Mice
Microscopy, Confocal
Molecular Conformation
Optical properties
Spectrometry, Fluorescence
Utilities
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Summary:The fascinating biological activity of gold coordination compounds has led to the development of a wide range of complexes. The precise biological action of such species is often poorly understood and the ability to map gold distribution in cellular environments is key. This article discusses the recent progress in luminescent Au( i ) complexes whilst considering their utility in bioimaging and therapeutics. This article discusses the recent progress in luminescent Au( i ) complexes whilst considering their utility in bioimaging and therapeutics.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc03259d