Imatinib intermediate as a two in one dual channel sensor for the recognition of Cu²⁺ and I⁻ ions in aqueous media and its practical applications

An imatinib intermediate, 6-methyl-N-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diaminepyridopyrimidotoluidine (PPT-1), was developed for the colorimetric sensing of Cu(2+) ions in aqueous solution. With Cu(2+), the receptor PPT-1 showed a highly selective naked-eye detectable color change from col...

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Bibliographic Details
Published in:Dalton transactions : an international journal of inorganic chemistry 2014-09, Vol.43 (35), p.13299-13306
Main Authors: Patil, Samadhan R, Nandre, Jitendra P, Jadhav, Devising, Bothra, Shilpa, Sahoo, S K, Devi, Manisha, Pradeep, Chullikkattil P, Mahulikar, Pramod P, Patil, Umesh D
Format: Article
Language:English
Subjects:
Benzamides - chemistry
Colorimetry - methods
Copper - analysis
Imatinib Mesylate
Iodides - analysis
Ions
Piperazines - chemistry
Pyrimidines - chemistry
Solutions - analysis
Water - analysis
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Summary:An imatinib intermediate, 6-methyl-N-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diaminepyridopyrimidotoluidine (PPT-1), was developed for the colorimetric sensing of Cu(2+) ions in aqueous solution. With Cu(2+), the receptor PPT-1 showed a highly selective naked-eye detectable color change from colorless to red over the seventy other tested cations. The colorimetric sensing ability of PPT-1 was successfully utilized in the preparation of test strips and supported silica for the real samples analysis to detect Cu(2+) ions from 100% aqueous environment. Moreover, the iodide-sensing ability of receptor PPT-1 was explored among the ten examined anions.
ISSN:1477-9234
DOI:10.1039/c4dt01516a