Wide Field Super-Resolution Surface Imaging through Plasmonic Structured Illumination Microscopy

We experimentally demonstrate a wide field surface plasmon (SP) assisted super-resolution imaging technique, plasmonic structured illumination microscopy (PSIM), by combining tunable SP interference (SPI) with structured illumination microscopy (SIM). By replacing the laser interference fringes in c...

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Bibliographic Details
Published in:Nano letters 2014-08, Vol.14 (8), p.4634-4639
Main Authors: Wei, Feifei, Lu, Dylan, Shen, Hao, Wan, Weiwei, Ponsetto, Joseph Louis, Huang, Eric, Liu, Zhaowei
Format: Article
Language:English
Subjects:
Biological and medical sciences
Collective excitations (including excitons, polarons, plasmons and other charge-density excitations)
Condensed matter: electronic structure, electrical, magnetic, and optical properties
Electronic structure and electrical properties of surfaces, interfaces, thin films and low-dimensional structures
Exact sciences and technology
Fundamental and applied biological sciences. Psychology
General aspects, investigation technics, apparatus
Physics
Surface and interface electron states
Tissues, organs and organisms biophysics
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Summary:We experimentally demonstrate a wide field surface plasmon (SP) assisted super-resolution imaging technique, plasmonic structured illumination microscopy (PSIM), by combining tunable SP interference (SPI) with structured illumination microscopy (SIM). By replacing the laser interference fringes in conventional SIM with SPI patterns, PSIM exhibits greatly enhanced resolving power thanks to the unique properties of SP waves. This PSIM technique is a wide field, surface super-resolution imaging technique with potential applications in the field of high-speed biomedical imaging.
ISSN:1530-6984
1530-6992
DOI:10.1021/nl501695c