Multicystic dysplastic kidney: A retrospective study

Objective To report the renal structural and functional anomalies in children with multicystic dysplastic kidneys. Methods Retrospective descriptive analysis of 47 children with multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years. Results Antenatal diagnosis of...

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Bibliographic Details
Published in:Indian pediatrics 2014-08, Vol.51 (8), p.641-643
Main Authors: Sharada, Sathish, Vijayakumar, Mahalingam, Nageswaran, Prahlad, Ekambaram, Sudha, Udani, Amish
Format: Article
Language:English
Subjects:
Female
Humans
India - epidemiology
Kidney - physiopathology
Male
Maternal and Child Health
Medicine
Medicine & Public Health
Multicystic Dysplastic Kidney - diagnosis
Multicystic Dysplastic Kidney - epidemiology
Multicystic Dysplastic Kidney - physiopathology
Pediatric Surgery
Pediatrics
Proteinuria
Research Brief
Retrospective Studies
Vesico-Ureteral Reflux
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Summary:Objective To report the renal structural and functional anomalies in children with multicystic dysplastic kidneys. Methods Retrospective descriptive analysis of 47 children with multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years. Results Antenatal diagnosis of multicystic dysplastic kidney was made in 34 (72.3%) patients. On follow up of 31 children for more than 12 months, 21 (68%) had involution, 4 [13%] had non-regression, and 4 (13%) were nephrectomized. Vesico-ureteric reflux ( n=13; 28%) was the commonest renal abnormality. The serum creatinine values were higher ( P =0.006) in children with contralateral reflux. Sub-nephrotic proteinuria was noted in 9 (29%) and was significantly associated with complete involution ( P =
ISSN:0019-6061
0974-7559
DOI:10.1007/s13312-014-0467-z