Fractional anisotropy asymmetry and the side of seizure origin for partial onset-temporal lobe epilepsy

• Published in: Computerized medical imaging and graphics 2014-09, Vol.38 (6), p.481-489
• Main Authors: Li, Hai, Xue, Zhong, Dulay, Mario F, Verma, Amit, Karmonik, Christof, Grossman, Robert G, Wong, Stephen T
• Format: Article
• Language: English
• Subjects: Adult; Anisotropy; Applied sciences; Artificial intelligence; Biological and medical sciences; Central nervous system; Central neurotransmission. Neuromudulation. Pathways and receptors; Computer science; control theory; systems; Diffusion Tensor Imaging; Diffusion tensor imaging (DTI); Epilepsy, Temporal Lobe - diagnosis; Epilepsy, Temporal Lobe - physiopathology; Exact sciences and technology; Fractional anisotropy asymmetry (FAA); Fundamental and applied biological sciences. Psychology; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Internal Medicine; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging; Medical sciences; Middle Aged; Nervous system; Nervous system (semeiology, syndromes); Neurology; Other; Pattern recognition. Digital image processing. Computational geometry; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Seizures - diagnosis; Seizures - diagnostic imaging; Seizures - physiopathology; Temporal lobe epilepsy; Tract-based spatial statistics (TBSS); Ultrasonography; Vertebrates: nervous system and sense organs
• ISSN: 0895-6111; 1879-0771
• DOI: 10.1016/j.compmedimag.2014.06.009

Highlights • Fractional anisotropy asymmetry (FAA) relates to the side of seizure origin for partial onset temporal lobe epilepsy (TLE). • FAA quantifies the asymmetry of white matter (WM) diffusivity of region pairs between the left and right hemispheres. • FAA values for superior, middle, and inferior temporal WM are significantly different between the left and right TLE patients.