Estimated impact and cost-effectiveness of rotavirus vaccination in India: Effects of geographic and economic disparities

Highlights • Modeled the impact and cost-effectiveness of rotavirus vaccination accounting for socio-economic and geographic disparities. • Nationally, an estimated 35,000 deaths could be averted with the introduction of rotavirus vaccines. • A vaccination program would be cost-effective, with regio...

Full description

Saved in:
Bibliographic Details
Published in:Vaccine 2014-08, Vol.32, p.A140-A150
Main Authors: Rheingans, Richard, Anderson, John D, Anderson, Benjamin, Chakraborty, Poulomy, Atherly, Deborah, Pindolia, Deepa
Format: Article
Language:English
Subjects:
Allergy and Immunology
Child, Preschool
Children & youth
Cost of Illness
Cost-Benefit Analysis
Cost-effectiveness
Diarrhea
Disparities
Economics
Equity
Geography
Health Care Costs
Health risks
Health Status Disparities
Heterogeneity
Humans
Immunization
India
India - epidemiology
Infant
Models, Economic
Mortality risk
Rotavirus
Rotavirus Infections - economics
Rotavirus Infections - mortality
Rotavirus Infections - prevention & control
Rotavirus Vaccines - economics
Socioeconomic Factors
Socioeconomics
Subpopulations
Vaccination
Vaccination - economics
Vaccines
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Modeled the impact and cost-effectiveness of rotavirus vaccination accounting for socio-economic and geographic disparities. • Nationally, an estimated 35,000 deaths could be averted with the introduction of rotavirus vaccines. • A vaccination program would be cost-effective, with regional ICERs ranging from $105 to $298/DALY averted (6489–18,416 INR/DALY averted) and the most favorable ratios in the high mortality regions and states. • Given low coverage, the poorest and most susceptible children are least likely to benefit from vaccination. • Reductions in socio-economic and geographic disparities could substantially improve the impact of a rotavirus vaccination.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2014.05.073