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Effect of tinidazole on the human oral microflora: A comparison between high single and low repeated doses

Tinidazole capsules were given orally in doses of 150 mg every 12 h for 7 days to ten patients and as a 1 g single dose to another ten patients. In the ten patients receiving repeated 150 mg doses, only minor changes in the oral microflora were observed, while distinct changes in the numbers of anae...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 1982-01, Vol.10 (3), p.157-164
Main Authors: Heimdahl, A, von Konow, L, Nord, CE
Format: Article
Language:English
Online Access:Get full text
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Summary:Tinidazole capsules were given orally in doses of 150 mg every 12 h for 7 days to ten patients and as a 1 g single dose to another ten patients. In the ten patients receiving repeated 150 mg doses, only minor changes in the oral microflora were observed, while distinct changes in the numbers of anaerobic and aerobic bacteria were noticed in the ten patients receiving a 1 g single dose.
ISSN:0305-7453