Investigation of the 8-hydroxy-2′-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli

Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2′-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant c...

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Bibliographic Details
Published in:Veterinary parasitology 2014-08, Vol.204 (3-4), p.388-391
Main Authors: Ciftci, Gulay, Ural, Kerem, Aysul, Nuran, Cenesiz, Sena, Guzel, Murat, Pekmezci, Didem, Sogut, Mehtap Ünlü
Format: Article
Language:English
Subjects:
8-Hydroxy-2′-deoxyguanosine
Animals
Antioxidants - analysis
Babesia - physiology
Babesia vogeli
Babesiosis - metabolism
Deoxyguanosine - analogs & derivatives
Deoxyguanosine - blood
DNA, Protozoan - genetics
Dog Diseases - metabolism
Dogs
Nitric oxide
Nitric Oxide - blood
Oxidative Stress
Total antioxidant capacity
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Summary:Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2′-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P0.05).
ISSN:0304-4017
1873-2550
DOI:10.1016/j.vetpar.2014.05.002