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The homeobox gene EMX2 is a prognostic and predictive marker in malignant pleural mesothelioma
Highlights • Low-EMX2 expression is a negative prognostic factor in mesothelioma. • High-EMX2 expression is associated with no benefice of neoadjuvant chemotherapy. • EMX2 expression is associated with IMIG stage and smoking history.
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| Published in: | Lung cancer (Amsterdam, Netherlands) Netherlands), 2014-09, Vol.85 (3), p.465-471 |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c520t-99586d076315fa5b8a6d3b5de93a45384afdd14f798f59449d1027b1c2f025193 |
| container_end_page | 471 |
| container_issue | 3 |
| container_start_page | 465 |
| container_title | Lung cancer (Amsterdam, Netherlands) |
| container_volume | 85 |
| creator | Giroux Leprieur, Etienne Hirata, Tomomi Mo, Minli Chen, Zhao Okamoto, Junichi Clement, Genevieve Li, Hui Wislez, Marie Jablons, David M He, Biao |
| description | Highlights • Low-EMX2 expression is a negative prognostic factor in mesothelioma. • High-EMX2 expression is associated with no benefice of neoadjuvant chemotherapy. • EMX2 expression is associated with IMIG stage and smoking history. |
| doi_str_mv | 10.1016/j.lungcan.2014.06.018 |
| format | article |
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Solid tumors. Tumors in childhood (general aspects) ; Neoadjuvant chemotherapy ; Neoplasm Staging ; Overall survival ; Pleural Neoplasms - genetics ; Pleural Neoplasms - mortality ; Pleural Neoplasms - pathology ; Pleural Neoplasms - therapy ; Pneumology ; Predictive marker ; Prognosis ; Progression-free survival ; Pulmonary/Respiratory ; Transcription Factors - genetics ; Tumors ; Tumors of the respiratory system and mediastinum</subject><ispartof>Lung cancer (Amsterdam, Netherlands), 2014-09, Vol.85 (3), p.465-471</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2014 Elsevier Ireland Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Ireland Ltd. 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Solid tumors. 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| ispartof | Lung cancer (Amsterdam, Netherlands), 2014-09, Vol.85 (3), p.465-471 |
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| language | eng |
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| source | Elsevier |
| subjects | Aged Aged, 80 and over Biological and medical sciences Biomarkers Combined Modality Therapy Disease Progression EMX2 Female Gene Expression Hematology, Oncology and Palliative Medicine Homeodomain Proteins - genetics Humans Lung Neoplasms - genetics Lung Neoplasms - mortality Lung Neoplasms - pathology Lung Neoplasms - therapy Male Medical sciences Mesothelioma Mesothelioma - genetics Mesothelioma - mortality Mesothelioma - pathology Mesothelioma - therapy Mesothelioma, Malignant Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoadjuvant chemotherapy Neoplasm Staging Overall survival Pleural Neoplasms - genetics Pleural Neoplasms - mortality Pleural Neoplasms - pathology Pleural Neoplasms - therapy Pneumology Predictive marker Prognosis Progression-free survival Pulmonary/Respiratory Transcription Factors - genetics Tumors Tumors of the respiratory system and mediastinum |
| title | The homeobox gene EMX2 is a prognostic and predictive marker in malignant pleural mesothelioma |
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