Monoclonal antibodies to discrete regions of human Glu sub(1)-plasminogen

In order to assess the importance of these regions in many of the chemical and functional properties of human plasminogen and plasmin, utilizing the native molecule, the authors have undertaken a program aimed at the generation of a series of monoclonal antibodies to these domains. Data are presente...

Full description

Saved in:
Bibliographic Details
Published in:Biochemistry (Easton) 1982-01, Vol.21 (23), p.5891-5897
Main Authors: Ploplis, V A, Cummings, H S, Castellino, F J
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In order to assess the importance of these regions in many of the chemical and functional properties of human plasminogen and plasmin, utilizing the native molecule, the authors have undertaken a program aimed at the generation of a series of monoclonal antibodies to these domains. Data are presented in this paper which show that antibodies of this type have been generated and can indeed bind to specific domain regions in plasminogen.
ISSN:0006-2960