cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl super(-)/HCO sub(3) super(-) exchanger

Complementary DNAs encoding two proteins that are related to the Band 3 Cl super(-)/HCO sub(3) super(-) exchanger, designated B3RP2 and B3RP3, have been isolated from rat stomach, brain, and kidney libraries. B3RP2 is 1234 amino acids in length and has a M sub(r) of 136,644. B3RP3 is 1227 amino acid...

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Bibliographic Details
Published in:The Journal of biological chemistry 1990-01, Vol.265 (1), p.462-471
Main Authors: Kudrycki, KE, Newman, PR, Shull, GE
Format: Article
Language:English
Online Access:Get full text
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Summary:Complementary DNAs encoding two proteins that are related to the Band 3 Cl super(-)/HCO sub(3) super(-) exchanger, designated B3RP2 and B3RP3, have been isolated from rat stomach, brain, and kidney libraries. B3RP2 is 1234 amino acids in length and has a M sub(r) of 136,644. B3RP3 is 1227 amino acids in length and has an M sub(r) or 135,405. B3RP2 and B3RP3 exhibit 52 and 50% amino acid identity to Band 3, respectively, and 56% identity to each other. The N-terminal cytoplasmic regions of B3RP2 and B3RP3, which span about 700 amino acids, are more extensive than that of Band 3.
ISSN:0021-9258