Migraine and perimenopause

Abstract Perimenopause and migraine are closely linked. The hormonal instability during the perimenopausal period not only causes vasomotor symptoms and mood disturbances, but also increases migraine incidence. Women do report new onset migraine during this period, but the increased incidence is rep...

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Bibliographic Details
Published in:Maturitas 2014-08, Vol.78 (4), p.277-280
Main Authors: Ibrahimi, Khatera, Couturier, Emile G.M, MaassenVanDenBrink, Antoinette
Format: Article
Language:English
Subjects:
Biological and medical sciences
CGRP
Estradiol
Estrogen Replacement Therapy - adverse effects
Gynecology. Andrology. Obstetrics
Hormones - metabolism
Humans
Internal Medicine
Medical sciences
Menopause
Menstruation
Migraine
Migraine Disorders - drug therapy
Migraine Disorders - etiology
Migraine Disorders - metabolism
Neurology
Obstetrics and Gynecology
Perimenopause - metabolism
Puberal and climacteric disorders (male and female)
Stroke - etiology
Vascular diseases and vascular malformations of the nervous system
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Summary:Abstract Perimenopause and migraine are closely linked. The hormonal instability during the perimenopausal period not only causes vasomotor symptoms and mood disturbances, but also increases migraine incidence. Women do report new onset migraine during this period, but the increased incidence is reported by women with menstrually related migraine (MRM). The hormonal fluctuations can be stabilized with hormone replacement therapy (HRT), while simultaneously improving the migraine in some patients. The increased stroke risk in women with migraine with aura (MA) should be taken into consideration when intending to treat perimenopausal women with migraine with HRT.
ISSN:0378-5122
1873-4111
DOI:10.1016/j.maturitas.2014.05.018