A commentary on the role of skin temperature on the effectiveness of ALA-PDT in Dermatology

Highlights • Elevating skin temperature could be an interesting approach to improving ALA-PDT of nodular BCC and other skin lesions. • Elevating skin temperature could induce a better ALA uptake. • Elevating skin temperature could induce a higher PpIX production into cells. • Elevating skin temperat...

Full description

Saved in:
Bibliographic Details
Published in:Photodiagnosis and photodynamic therapy 2014-09, Vol.11 (3), p.416-419
Main Author: Mordon, Serge, PhD
Format: Article
Language:English
Subjects:
5-ALA
Administration, Topical
Aminolevulinic Acid - administration & dosage
Aminolevulinic Acid - pharmacokinetics
Animals
Biological Availability
Daylight
Heating - methods
Hematology, Oncology and Palliative Medicine
Humans
Internal Medicine
Photochemotherapy
Photosensitizing Agents - administration & dosage
Photosensitizing Agents - pharmacokinetics
Protoporphyrin IX
Skin
Skin Absorption - physiology
Skin Temperature - physiology
Temperature
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Elevating skin temperature could be an interesting approach to improving ALA-PDT of nodular BCC and other skin lesions. • Elevating skin temperature could induce a better ALA uptake. • Elevating skin temperature could induce a higher PpIX production into cells. • Elevating skin temperature could increase the oxygen supply. • Different techniques can be used to perform an elevation of skin temperature.
ISSN:1572-1000
1873-1597
DOI:10.1016/j.pdpdt.2014.05.004