Diverse outcomes of Photodynamic Antimicrobial Chemotherapy on five Enterococcus faecalis strains

Highlights • Photogem alone was distinctly toxic to planktonic cells of Enterococcus faecalis. • Photogem-mediated PACT was effective against biofilms of all E. faecalis strains. • The efficacy of PACT on E. faecalis biofilms was strain-dependent. • Clinical outcomes of PACT on E. faecalis probably...

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Bibliographic Details
Published in:Photodiagnosis and photodynamic therapy 2014-09, Vol.11 (3), p.283-289
Main Authors: Silva, T.C., PhD, Pereira, A.F.F, Buzalaf, M.A.R, Machado, M.A.A.M, Crielaard, W, Deng, D.M
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - administration & dosage
Biofilm
Biofilms - drug effects
Biofilms - growth & development
Biofilms - radiation effects
Cell Proliferation - drug effects
Cell Proliferation - radiation effects
Cell Survival - drug effects
Cell Survival - radiation effects
Dose-Response Relationship, Drug
Enterococcus faecalis
Enterococcus faecalis - classification
Enterococcus faecalis - drug effects
Enterococcus faecalis - physiology
Hematology, Oncology and Palliative Medicine
Hematoporphyrins - administration & dosage
Internal Medicine
Light Emitting Diode
Photochemotherapy - methods
Photodynamic Antimicrobial Chemotherapy
Photosensitizing Agents - administration & dosage
Plankton - drug effects
Plankton - physiology
Planktonic cells
Species Specificity
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Summary:Highlights • Photogem alone was distinctly toxic to planktonic cells of Enterococcus faecalis. • Photogem-mediated PACT was effective against biofilms of all E. faecalis strains. • The efficacy of PACT on E. faecalis biofilms was strain-dependent. • Clinical outcomes of PACT on E. faecalis probably vary among different patients.
ISSN:1572-1000
1873-1597
DOI:10.1016/j.pdpdt.2014.04.003