Metabolomic (anthropometric and biochemical) indexes and metabolic syndrome in adolescents and young adults with intellectual disabilities

•We studied anthropometric and biochemical indexes named metabolomic-indexes, in persons with intellectual disabilities.•Metabolomic-indexes can significantly predict MetS occurrence.•Anthropometric and biochemical indexes must be corrected by height in order to increase the determination index on m...

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Bibliographic Details
Published in:Research in developmental disabilities 2014-11, Vol.35 (11), p.2987-2992
Main Authors: Ramos-Jiménez, Arnulfo, Hernández-Torres, Rosa Patricia, Wall-Medrano, Abraham, Villalobos-Molina, Rafael
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anthropometry
Arm - anatomy & histology
Arm circumference
Blood Glucose
Body Mass Index
Cardiovascular risk
Cholesterol - blood
Cholesterol, HDL - blood
Cross-Sectional Studies
Female
Hip
Humans
Intellectual Disability - complications
Male
Metabolic Syndrome - blood
Metabolic Syndrome - complications
Metabolic Syndrome - diagnosis
Metabolic syndrome index
Obesity
Organ Size
Skinfold Thickness
Skinfolds
Triglycerides - blood
Waist Circumference
Waist-Hip Ratio
Young Adult
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Summary:•We studied anthropometric and biochemical indexes named metabolomic-indexes, in persons with intellectual disabilities.•Metabolomic-indexes can significantly predict MetS occurrence.•Anthropometric and biochemical indexes must be corrected by height in order to increase the determination index on metabolic syndrome. The aim of the present study was to describe the use of combination of international standardized anthropometric parameters, along with biochemical parameters (metabolomic indexes) to identify metabolic syndrome (MetS), in persons with intellectual disabilities. We conducted a cross-sectional study of 42 adolescents and young adults with intellectual disabilities (aged 13–30years) who attend special schools in Ciudad Juárez, Chihuahua, México. The study included anthropometric (using the International Society for the Advancement of Kineanthropometry recommendations) and biochemical measures, and their combinations as metabolomic-indexes, that can significantly predict MetS occurrence in this vulnerable population. Waist circumference (WC) and relaxed arm circumference, both adjusted for height, have the highest correlation with MetS (R2=0.23–0.47, p
ISSN:0891-4222
1873-3379
DOI:10.1016/j.ridd.2014.07.050